Commentary (Slavin): Nonmyeloablative Preparative Regimens for Allogeneic Hematopoietic Transplantation
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چکیده
Champlin and colleagues have elegantly summarized the concept of nonmyeloablative stem cell transplantation (NST), stressing the importance of this newly emerging procedure for the treatment of patients with life-threatening malignant hematologic and nonhematologic diseases. This review does not include a description of the safety and efficacy of NST for the treatment of many life-threatening nonmalignant diseases for which no alternative therapy exists. This category encompasses a long list of genetic disorders, diseases caused by a deficiency of stem cell products, and syndromes associated with immune deficiency. However, discussion of these illnesses is beyond the scope of this review, which focuses on cancer.
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Nonmyeloablative allogeneic hematopoietic stem cell transplantation.
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